Biodirectional catheter

Technology

Revolutionizing Brain Cancer Treatment with Pinpoint Accuracy

At the heart of Ambusol’s breakthrough treatment for glioblastoma (GBM) lies our patented catheter technology—a state-of-the-art delivery system designed for unparalleled precision and control. Unlike conventional therapies that affect the entire body, our approach targets the tumor with laser-sharp accuracy, sparing healthy brain tissue and eliminating systemic side effects.

 

How Our Patented Catheter Works

The Ambusol catheter system is a sophisticated medical device that enables the direct administration and simultaneous extraction of our proprietary treatment solution. This innovative “push-pull” mechanism is what sets our therapy apart.

  • Precision Targeting: The catheter is surgically guided directly to the tumor site. Its unique design creates a hydrodynamically confined solution, acting like a surgical instrument at the cellular level. This ensures the treatment fluid acts only on the cancerous cells, creating a clean boundary between diseased and healthy tissue.
  • Controlled Bi-Directional Flow: The system allows clinicians to seamlessly switch between delivering the therapeutic solution and washing out the resulting necrotic (dead) tissue debris. This continuous clearance prevents buildup and allows for consistent, effective treatment.
  • Real-Time Monitoring and Safety: Integrated sensors, including a pressure monitor, provide real-time data on intracranial pressure. Combined with precise volume control, this significantly enhances patient safety by helping to avoid complications such as hemorrhage.

 

Key Advantages of the Ambusol Catheter System

  • Unmatched Precision: Offers laser-sharp demarcation between tumor and healthy cells, maximizing efficacy and safety.
  • Localized Treatment: Administers therapy directly into the tumor, preventing the widespread side effects common with chemotherapy and radiation.
  • Enhanced Efficacy: The simultaneous extraction of necrotic tissue improves the local treatment environment and may contribute to better outcomes.
  • Integrated Platform: The catheter is an integral part of our global IP portfolio, protected by multiple patent families, ensuring a durable competitive advantage.

 

A Complete Treatment in One Week

Traditional GBM treatments are a marathon of surgery, radiation, and chemotherapy, often lasting over 13 months and severely impacting quality of life. The Ambusol system, combined with our artificial amino acid treatment, condenses this arduous process into a single, 7-day regimen with no observed adverse side effects.

 

The Future: Personalized Treatment with AI

We are continuously advancing our catheter technology. Our ongoing development focuses on leveraging artificial intelligence (AI) to further personalize the treatment for each patient. This will allow us to fully customize the procedure, enhancing precision, maximizing comfort, and minimizing discomfort during an already challenging time for patients and their families.

Our catheter technology is more than just a delivery device; it is the enabling platform that makes a truly targeted, humane, and effective cancer treatment possible.